4-[2-Amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]-4-pyrimidinyl]-L-phenylalanine ethyl ester

CAS Registry Number®

1033805-22-9

CAS Name

4-[2-Amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]-4-pyrimidinyl]-L-phenylalanine ethyl ester

Molecular Formula

C27H26ClF3N6O3

Molecular Mass

574.98

Cite this Page

4-[2-Amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]-4-pyrimidinyl]-L-phenylalanine ethyl ester.   CAS Common Chemistry.   CAS, a division of the American Chemical Society, n.d.   http://commonchemistry.cas.org/detail?cas_rn=1033805-22-9 (retrieved 2024-11-21) (CAS RN: 1033805-22-9).  Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Other Names and Identifiers

InChI

InChI=1S/C27H26ClF3N6O3/c1-3-39-25(38)20(32)12-16-4-6-17(7-5-16)21-14-23(35-26(33)34-21)40-24(27(29,30)31)19-9-8-18(28)13-22(19)37-11-10-15(2)36-37/h4-11,13-14,20,24H,3,12,32H2,1-2H3,(H2,33,34,35)/t20-,24+/m0/s1

InChIKey

InChIKey=MDSQOJYHHZBZKA-GBXCKJPGSA-N

SMILES

[C@H](OC=1C=C(N=C(N)N1)C2=CC=C(C[C@@H](C(OCC)=O)N)C=C2)(C(F)(F)F)C3=C(C=C(Cl)C=C3)N4C=CC(C)=N4

Canonical SMILES

O=C(OCC)C(N)CC=1C=CC(=CC1)C=2N=C(N=C(OC(C3=CC=C(Cl)C=C3N4N=C(C=C4)C)C(F)(F)F)C2)N

Other Names for this Substance

  • L-Phenylalanine, 4-[2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]-4-pyrimidinyl]-, ethyl ester
  • 4-[2-Amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]-4-pyrimidinyl]-L-phenylalanine ethyl ester
  • Telotristat ethyl
  • LX 1606
  • (2S)-2-Amino-3-[4-[2-amino-6-[[(1R)-1-[4-chloro-2-(3-methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethyl]oxy]pyrimidin-4-yl]phenyl]propionic acid ethyl ester

View All

CAS INSIGHTSTM
Targeted protein degrader structure, illustration