Encorafenib

CAS Registry Number®

1269440-17-6

CAS Name

Encorafenib

Molecular Formula

C22H27ClFN7O4S

Molecular Mass

540.01

Cite this Page

Encorafenib.   CAS Common Chemistry.   CAS, a division of the American Chemical Society, n.d.   http://commonchemistry.cas.org/detail?cas_rn=1269440-17-6 (retrieved 2024-11-21) (CAS RN: 1269440-17-6).  Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Other Names and Identifiers

InChI

InChI=1S/C22H27ClFN7O4S/c1-12(2)31-11-16(17-6-7-25-21(28-17)26-10-13(3)27-22(32)35-4)20(29-31)15-8-14(23)9-18(19(15)24)30-36(5,33)34/h6-9,11-13,30H,10H2,1-5H3,(H,27,32)(H,25,26,28)/t13-/m0/s1

InChIKey

InChIKey=CMJCXYNUCSMDBY-ZDUSSCGKSA-N

SMILES

FC1=C(C=2C(=CN(C(C)C)N2)C3=NC(NC[C@@H](NC(OC)=O)C)=NC=C3)C=C(Cl)C=C1NS(C)(=O)=O

Canonical SMILES

O=C(OC)NC(C)CNC=1N=CC=C(N1)C2=CN(N=C2C=3C=C(Cl)C=C(NS(=O)(=O)C)C3F)C(C)C

Other Names for this Substance

  • Carbamic acid, N-[(1S)-2-[[4-[3-[5-chloro-2-fluoro-3-[(methylsulfonyl)amino]phenyl]-1-(1-methylethyl)-1H-pyrazol-4-yl]-2-pyrimidinyl]amino]-1-methylethyl]-, methyl ester
  • LGX 818
  • (S)-Methyl [1-[[4-[3-[5-chloro-2-fluoro-3-(methylsulfonamido)phenyl]-1-isopropyl-1H-pyrazol-4-yl]pyrimidin-2-yl]amino]propan-2-yl]carbamate
  • NVP-LGX 818NXA
  • Encorafenib

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CAS INSIGHTSTM
Targeted protein degrader structure, illustration