Tipifarnib

CAS Registry Number®

192185-72-1

CAS Name

Tipifarnib

Molecular Formula

C27H22Cl2N4O

Molecular Mass

489.40

Cite this Page

Tipifarnib.   CAS Common Chemistry.   CAS, a division of the American Chemical Society, n.d.   http://commonchemistry.cas.org/detail?cas_rn=192185-72-1 (retrieved 2024-11-21) (CAS RN: 192185-72-1).  Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Compound Properties

  • Melting Point (1)

    234 °C

Source(s)

Other Names and Identifiers

InChI

InChI=1S/C27H22Cl2N4O/c1-32-16-31-15-25(32)27(30,18-6-9-20(28)10-7-18)19-8-11-24-23(13-19)22(14-26(34)33(24)2)17-4-3-5-21(29)12-17/h3-16H,30H2,1-2H3/t27-/m1/s1

InChIKey

InChIKey=PLHJCIYEEKOWNM-HHHXNRCGSA-N

SMILES

[C@](N)(C=1C=C2C(=CC(=O)N(C)C2=CC1)C3=CC(Cl)=CC=C3)(C=4N(C)C=NC4)C5=CC=C(Cl)C=C5

Canonical SMILES

O=C1C=C(C=2C=CC=C(Cl)C2)C=3C=C(C=CC3N1C)C(N)(C4=CC=C(Cl)C=C4)C5=CN=CN5C

Other Names for this Substance

  • 2(1H)-Quinolinone, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-
  • 6-[(R)-Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
  • Tipifarnib
  • (R)-(+)-R 115777
  • Zarnestra

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CAS INSIGHTSTM
Targeted protein degrader structure, illustration