Tenofovir alafenamide

CAS Registry Number®

379270-37-8

CAS Name

Tenofovir alafenamide

Molecular Formula

C21H29N6O5P

Molecular Mass

476.47

Cite this Page

Tenofovir alafenamide.   CAS Common Chemistry.   CAS, a division of the American Chemical Society, n.d.   http://commonchemistry.cas.org/detail?cas_rn=379270-37-8 (retrieved 2024-11-21) (CAS RN: 379270-37-8).  Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Compound Properties

  • Melting Point (1)

    117-120 °C

Source(s)

Other Names and Identifiers

InChI

InChI=1S/C21H29N6O5P/c1-14(2)31-21(28)16(4)26-33(29,32-17-8-6-5-7-9-17)13-30-15(3)10-27-12-25-18-19(22)23-11-24-20(18)27/h5-9,11-12,14-16H,10,13H2,1-4H3,(H,26,29)(H2,22,23,24)/t15-,16+,33+/m1/s1

InChIKey

InChIKey=LDEKQSIMHVQZJK-CAQYMETFSA-N

SMILES

C([C@H](OCP(OC1=CC=CC=C1)(N[C@H](C(OC(C)C)=O)C)=O)C)N2C=3C(N=C2)=C(N)N=CN3

Canonical SMILES

O=C(OC(C)C)C(NP(=O)(OC=1C=CC=CC1)COC(C)CN2C=NC=3C(=NC=NC32)N)C

Other Names for this Substance

  • L-Alanine, N-[(S)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester
  • GS 7340
  • Tenofovir alafenamide
  • 4: PN: WO2016077321 SEQID: 4 claimed sequence
  • Vemlidy

Deleted or Replaced CAS Registry Numbers

377091-31-1

CAS INSIGHTSTM
Targeted protein degrader structure, illustration