Regorafenib

CAS Registry Number®

755037-03-7

CAS Name

Regorafenib

Molecular Formula

C21H15ClF4N4O3

Molecular Mass

482.82

Cite this Page

Regorafenib.   CAS Common Chemistry.   CAS, a division of the American Chemical Society, n.d.   http://commonchemistry.cas.org/detail?cas_rn=755037-03-7 (retrieved 2024-11-21) (CAS RN: 755037-03-7).  Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Compound Properties

  • Melting Point (1)

    206-207 °C

Source(s)

Other Names and Identifiers

InChI

InChI=1S/C21H15ClF4N4O3/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/h2-10H,1H3,(H,27,31)(H2,29,30,32)

InChIKey

InChIKey=FNHKPVJBJVTLMP-UHFFFAOYSA-N

SMILES

O(C=1C=C(C(NC)=O)N=CC1)C2=CC(F)=C(NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=O)C=C2

Canonical SMILES

O=C(NC1=CC=C(Cl)C(=C1)C(F)(F)F)NC2=CC=C(OC=3C=CN=C(C3)C(=O)NC)C=C2F

Other Names for this Substance

  • 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-
  • 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide
  • 4-[4-[N′-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic acid methylamide
  • Regorafenib
  • BAY 73-4506

View All

Deleted or Replaced CAS Registry Numbers

1219951-07-1, 1370461-45-2

CAS INSIGHTSTM
Targeted protein degrader structure, illustration