Crizotinib

CAS Registry Number®

877399-52-5

CAS Name

Crizotinib

Molecular Formula

C21H22Cl2FN5O

Molecular Mass

450.34

Cite this Page

Crizotinib.   CAS Common Chemistry.   CAS, a division of the American Chemical Society, n.d.   http://commonchemistry.cas.org/detail?cas_rn=877399-52-5 (retrieved 2024-12-03) (CAS RN: 877399-52-5).  Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Compound Properties

  • Melting Point (1)

    192 °C

Source(s)

Other Names and Identifiers

InChI

InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1

InChIKey

InChIKey=KTEIFNKAUNYNJU-GFCCVEGCSA-N

SMILES

O([C@H](C)C1=C(Cl)C(F)=CC=C1Cl)C2=CC(C3=CN(N=C3)C4CCNCC4)=CN=C2N

Canonical SMILES

FC1=CC=C(Cl)C(=C1Cl)C(OC=2C=C(C=NC2N)C=3C=NN(C3)C4CCNCC4)C

Other Names for this Substance

  • 2-Pyridinamine, 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-
  • 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine
  • [3-[[(R)-1-(2,6-Dichloro-3-fluorophenyl)ethyl]oxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-yl]amine
  • PF 2341066
  • PF 02341066

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Deleted or Replaced CAS Registry Numbers

912279-98-2

CAS INSIGHTSTM
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