Ruxolitinib

CAS Registry Number®

941678-49-5

CAS Name

Ruxolitinib

Molecular Formula

C17H18N6

Molecular Mass

306.36

Cite this Page

Ruxolitinib.   CAS Common Chemistry.   CAS, a division of the American Chemical Society, n.d.   http://commonchemistry.cas.org/detail?cas_rn=941678-49-5 (retrieved 2024-11-21) (CAS RN: 941678-49-5).  Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Compound Properties

  • Melting Point (1)

    88 °C

Source(s)

Other Names and Identifiers

InChI

InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1

InChIKey

InChIKey=HFNKQEVNSGCOJV-OAHLLOKOSA-N

SMILES

[C@H](CC#N)(N1C=C(C2=C3C(=NC=N2)NC=C3)C=N1)C4CCCC4

Canonical SMILES

N#CCC(N1N=CC(=C1)C=2N=CN=C3NC=CC32)C4CCCC4

Other Names for this Substance

  • 1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, (βR)-
  • (βR)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile
  • Ruxolitinib
  • INCB 018424
  • (3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile

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Deleted or Replaced CAS Registry Numbers

1138325-12-8

CAS INSIGHTSTM
Targeted protein degrader structure, illustration